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Carpal tunnel syndrome is the most common nerve compression problem of the upper extremity. It happens when the median nerve gets compressed in the elbow, commonly by swollen tendons and repetitive use. In addition, we frequently see it in patients with neck problems, also known as double crush syndrome. Carpal tunnel syndrome process affects about 1 percent of the general population and 5 percent of the working population and surgical treatment for carpal tunnel syndrome is the most frequent surgery of the hand and wrist. However, do all of these patients need surgery? In our clinical experience, a new technique called nerve hydrodissection may be a better answer for some patients. Rather than open surgery, this procedure can be performed by a doctor using a needle under careful ultrasound imaging guidance. Small amounts of fluid are injected around the nerve to “free up” the median nerve (which can become scarred and adherent to it’s surrounding tendons). This allows the nerve to glide easier and many times has the same effect as a surgical release, the numbness, tingling, and pain go away. We have also used Regenexx-SCP to perform this procedure, in hopes that the stem cell plasma will also help the nerve repair. The video above shows an ultrasound cross-section of the wrist. The median nerve is the big oval structure in the middle. The needle can be seen injecting fluid around the nerve (the dark material that seems to grow around the oval). Again, since this is done through a needle without cutting or damaging important ligaments in the writs, recovery time is much less than surgery.

Patient Case Report: KM is a 36 YOF with arm pain for 2 years who had an EMG/Nerve Conduction Study, brain MRI and cervical MRI along with physical therapy which didn’t help. The patient started on a fibromyalgia treatment program and was eventually referred for a diagnostic ultrasound to differentiate between tendon vs nerve dysfunction in the arms. Diagnostic ultrasound showed normal tendons, but swelling of the ulnar nerve proximal to the flexor heads at the cubital tunnel and slight swelling of the ulnar nerve at the wrist (she felt this area most at work when the wrist was resting on her drafting table). She underwent a diagnostic numbing injection of the ulnar nerve under ultrasound guidance with decreased pain at the elbow and wrist. At the same appointment, nerve hydrodissection made more room for her nerve through the cubital tunnel and around the wrist flexor heads by dissecting the tissue from around her nerve (also called hydrogenolysis). She reported 100% relief of her pain.

In this case, the ulnar nerve at the elbow was treated (not carpal tunnel at the wrist). This patient’s only other option would have been a risky surgery where the ulnar nerve is moved to a different location (ulnar transposition).



This one-on-one evaluation will help you understand: 


  • - Candidacy Grade: Good / Fair / Poor
  • - Which Regenexx procedure would be best for optimal results
  • - An understanding of diagnosis/prognosis
  • - Direction of best care
  • - Can be performed in-person or by telemedicine visit 

An evaluation is critical to understanding the underlying problems and selecting the best treatment plan that will help you get back to the things you love, without pain and surgery.