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Pudendal Neuralgia Treatment

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Pudendal neuralgia is a rare but life-altering condition where there is chronic pain in the pelvic region, often affecting daily activities and quality of life. This condition arises from irritation or damage to the pudendal nerve, which is critical in providing sensation to the perineum, genitals, and surrounding areas. 

People with pudendal neuralgia may experience intense discomfort during activities like sitting, exercising, or even simple movements, making it challenging to carry out routine tasks. This article will help you understand the causes, symptoms, and treatments for pudendal neuralgia.

Understanding Pudendal Neuralgia

Pudendal neuralgia is a chronic and debilitating pain condition that affects the pudendal nerve, a major nerve in the pelvis. This nerve provides sensation to the genital and perineal areas and supports pelvic floor muscles. Individuals with pudendal neuralgia often describe the pain as burning, sharp, or stabbing, which can worsen with sitting and improve with standing or lying down.

Possible Causes: Pudendal neuralgia can result from various factors, including the following:

  • Nerve compression: Prolonged sitting or cycling can compress the pudendal nerve.
  • Trauma or injury: Pelvic surgeries or childbirth may damage the nerve.
  • Inflammation: Conditions like endometriosis or infections can inflame nearby structures, irritating the nerve.
  • Chronic strain: Some activities or habits can stress the pelvic floor muscles.

Risk Factors: Certain individuals are more predisposed to pudendal neuralgia, such as:

  • Athletes who engage in repetitive pelvic movements, such as cyclists.
  • People with prior pelvic surgeries or injuries.
  • Women, following childbirth complications.
  • Individuals with conditions like pelvic floor dysfunction or chronic constipation.

How Is Pudendal Neuralgia Diagnosed?

Diagnosing pudendal neuralgia requires a thorough assessment, as its symptoms often overlap with other pelvic conditions. A detailed medical history, physical examination, and specialized diagnostic tools are used to identify the condition and rule out other causes of pelvic pain.

Medical History and Symptom Assessment

The diagnostic process typically begins with discussing the patient’s symptoms, lifestyle, and medical history. Key indicators include chronic pelvic pain that worsens with sitting and improves with standing and pain localized along the pudendal nerve’s distribution.

Diagnostic Techniques

  • Magnetic resonance imaging (MRI): MRI scans evaluate the pelvic region and identify structural abnormalities, such as nerve entrapment, vascular compression, or surrounding tissue damage. Advanced imaging techniques like MR neurography may provide a clearer view of the pudendal nerve and its branches.
  • Vaginal or rectal exam: A physical examination of the pelvic area is often performed to assess tenderness or pain along the pudendal nerve. During the exam, pressure may be applied to specific anatomical landmarks, such as the ischial spine or Alcock’s canal, to provoke symptoms.
  • Electromyography (EMG): EMG tests evaluate the electrical activity of the pelvic floor muscles innervated by the pudendal nerve. This can help detect nerve dysfunction, including signs of compression or damage, which may contribute to the patient’s symptoms.

Conditions Associated with Pudendal Neuralgia

Pudendal neuralgia often coexists with other pelvic or nerve-related conditions, complicating its diagnosis and management. Understanding these associated conditions can help clinicians provide comprehensive care.

Sciatica

Disc herniation, disc protrusion, overgrowth of the facet joint, and thickening of the ligaments can result in nerve root compression or irritation, causing symptoms of sciatic compression. Some causes of sciatic compression can be interrelated with the following conditions: Degenerative disc disease, Spinal stenosis, damage or injuries to the discs, spondylolisthesis, piriformis syndrome, osteoarthritis. The symptoms of sciatica include pain in the lower back, buttock, and down your leg, numbness and weakness in low back, buttock, leg, and/or feet, pain increase with movement, “Pins and needles” feeling in your legs, toes, or feet., loss of bowel control, and incontinence. Sciatica can be treated…

Read More About Sciatica

This is not a complete list, so please email, call, or text if you have questions about whether you are a candidate for pudendal neuralgia treatment.

  • Coccygodynia: Pain in the tailbone (coccyx) is a common overlapping condition, as the coccygeal region is anatomically close to the pudendal nerve. Injury, prolonged sitting, or trauma to the tailbone can exacerbate pudendal nerve pain.
  • Vulvodynia: In women, chronic pain in the vulvar region can coexist with pudendal neuralgia. The two conditions share similar symptom profiles, including burning or stabbing pain, making them challenging to differentiate.
  • Prostatitis: In men, chronic prostatitis or pelvic pain syndrome may involve pudendal nerve irritation. This condition can cause pain radiating to the perineum and genitals, resembling pudendal neuralgia.
  • Pelvic Floor Dysfunction: Tightness, weakness, or imbalance in the pelvic floor muscles often accompanies pudendal neuralgia. This dysfunction can both contribute to and result from pudendal nerve irritation, creating a cycle of chronic pain.
  • Sacroiliac Joint Dysfunction (SIJ): Instability of the SIJ can cause tightening of the surrounding muscles of the pelvis that assist in stabilizing the SIJ. This tightening can, in turn, cause musculature compression around the pudendal nerve, leading to compressive neuropathy of the pudendal nerve.

Treatment Options Used for Pudendal Neuralgia

Pudendal neuralgia treatments focus on alleviating pain, reducing nerve irritation, and improving overall quality of life. A multidisciplinary approach often provides the best results, incorporating medical, therapeutic, and regenerative options.

Medications

Neuropathic pain medications, such as gabapentin, pregabalin, or tricyclic antidepressants, are often prescribed to alleviate nerve-related pain. Nonsteroidal anti-inflammatory drugs (NSAIDs) may also help manage symptoms. 

However, it is important to be aware of their potential side effects, including gastrointestinal issues, cardiovascular risks, kidney damage, and increased blood pressure.

Physical Therapy

Specialized pelvic floor physical therapy focuses on relaxing tight muscles, improving posture, and enhancing pelvic alignment to reduce nerve compression.

Nerve Blocks

Pudendal nerve blocks involve injecting an anesthetic and corticosteroids near the nerve to reduce inflammation and relieve temporary pain. These can also help confirm the diagnosis.

PRP Therapy

Platelet-rich plasma (PRP) therapy injects concentrated growth factors from the patient’s blood to promote healing and tissue repair around the pudendal nerve.

Why Choose PRP Therapy Over Conventional Treatments

PRP therapy is gaining popularity due to its minimally invasive nature, ability to target the root cause of pain, and regenerative potential. Unlike temporary solutions such as nerve blocks or medications, PRP promotes natural healing, offering a longer-lasting resolution.

Minimally Invasive Techniques

PRP therapy involves using the body’s natural healing properties without surgery or extensive recovery time. This makes it an attractive option for patients seeking an alternative to invasive procedures.

Targeted Pain Relief

By delivering concentrated growth factors directly to the damaged nerve or surrounding tissues, PRP provides localized pain relief and supports nerve repair, reducing the need for systemic medications.

With its growing success rate and ability to address the underlying condition, PRP therapy is an excellent choice for those with severe or treatment-resistant pudendal neuralgia.

Conditions That PRP Injections Can Treat

PRP injections are used to manage various conditions, offering regenerative benefits to both nerve and musculoskeletal injuries.

Pudendal Neuralgia

PRP injections target the underlying damage contributing to pudendal nerve pain by promoting healing and reducing inflammation.

Trigeminal Neuralgia

PRP may reduce nerve irritation in trigeminal neuralgia, alleviating the facial pain associated with this condition.

Osteoarthritis

PRP can improve joint function and reduce inflammation in osteoarthritis, slowing cartilage degradation.

Rotator Cuff Tears

For partial tears, PRP therapy accelerates tissue repair and decreases pain, potentially avoiding surgery.

Tendonitis

PRP supports the healing of inflamed or injured tendons, improving function and reducing discomfort.

The Process of Regenerative Treatment for Pudendal Neuralgia

PRP therapy for pudendal neuralgia is a structured process designed for maximum safety and efficacy.

Before

  • Initial consultation to discuss all symptoms and a detailed hands-on physical examination.
  • Imaging studies review (e.g., MRI or ultrasound) to pinpoint the target area.
  • Blood draw to prepare the PRP solution.
    • Not all PRP is created equal. The physician will order correct dosing, and our state-of-the-art laboratory will process it to ensure the highest quality PRP produced to maximize your outcome!
  • During preparation, patients are informed about the procedure and any necessary precautions.

During

  • The PRP injection is administered under precision guidance utilizing the most advanced imaging modalities such as musculoskeletal ultrasound and fluoroscopic image guidance. 
  • The area is numbed with a local anesthetic for comfort.
    • IV conscious sedation is utilized during the procedure to maximize the patient’s comfort and allows the physician to target the most sensitive areas of the pudendal nerve.
  • PRP is injected into the targeted region, stimulating tissue repair and nerve healing.
  • Patients may experience mild soreness immediately after the injection.

After

  • Post-procedure care includes avoiding strenuous activities for a few days.
  • Follow-up appointments monitor progress and determine if additional sessions are needed.
  • Symptom improvement typically begins within weeks and continues over several months.

Side Effects: Temporary soreness, swelling, or mild bruising at the injection site.

Recovery Time: Most patients resume normal activities within one to two days.

Choose the Right Treatment for Pudendal Neuralgia

Finding the most effective treatment for pudendal neuralgia involves understanding your unique needs and exploring innovative options like PRP therapy. By combining minimally invasive techniques with targeted pain relief, PRP offers hope for long-lasting recovery. 

Am I a Candidate?

To answer this question, fill out the candidate form below to request a new patient evaluation, and a patient advocate will reach out to you to determine your next steps. Your one-hour, in-office or telemedicine evaluation will be with one of the world’s experts in the field of Interventional Orthopedics.