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Non-Surgical Peripheral Neuropathy Treatment

Advanced Non-surgical Solutions for Peripheral Nerve Injuries

Am I a Candidate?

Peripheral nerves are critical to your body’s movement and function. Unfortunately, they can easily be damaged. Peripheral neuropathy creates a multitude of symptoms that limit your function and overall performance. Helping these nerves to repair and restoring their function is what we do. We have created a non-surgical minimally invasive (image-guided injection) procedure that uses the most advanced autologous biologic (healing growth factors from your own body) to enhance nerve regeneration without the need for more risky and invasive surgery.

Centeno-Schultz Clinic has a range of procedures developed to help patients avoid surgeries and epidural steroid injections that are meant to treat peripheral neuropathy and injuries. These procedures utilize the patient’s own natural growth factors or bone marrow concentrate to treat conditions and injuries such as:

  • brachial plexus injuries,
  • cubital tunnel syndrome (ulnar neuropathy),
  • radial nerve palsy,
  • carpal tunnel syndrome (median neuropathy),
  • pudendal neuropathy,
  • peroneal nerve entrapment,
  • tibial nerve entrapment,
  • Baxter’s neuropathy,
  • trigeminal neuralgia.

This is not a complete list, so please emailcall, or text if you have questions about whether you are a candidate for peripheral neuropathy treatment.

Signs and Symptoms of Peripheral Neuropathy

  • Burning Pain
  • Numbness or Tingling
  • Muscular Weakness
  • Electric Sensations
  • Localized swelling
  • Allodynia – experience of pain from stimuli that isn’t normally painful
  • Hyperalgesia – increased pain from a stimulus that usually provokes pain

Carpal Tunnel Syndrome (Median Neuropathy)

When something causes the tunnel to narrow or the medial nerve somehow becomes compressed in the wrist, this can lead to carpal tunnel syndrome (CTS). CTS can be very uncomfortable, and the symptoms are pretty telling, including tingling, burning, or numbness in the thumb. At the Centeno-Schultz Clinic, we use a procedure called the Perc-CT SR Procedure.

Cubital Tunnel Syndrome (Ulnar Neuropathy)

Carpal tunnel syndrome is the most common nerve compression problem of the upper extremity. It happens when the median nerve gets compressed in the elbow, commonly by swollen tendons and repetitive use. At the Centeno-Schultz Clinic, nerve hydrodissection with the use of PRP or bone marrow concentrate containing stem cells has shown consistent and promising results.

Brachial Nerve Injuries

The brachial nerve extends to five nerve branches down the arm. The severity of a brachial plexus injury varies, depending on the part of the nerve that is injured and the extent of the injury. In some people, function and feeling returns to normal, while others may have lifelong disabilities because they can’t use or feel a part of their arm.

Are You A Candidate for our non-surgical peripheral neuropathy treatment?


Peripheral nerves can be injured multiple ways:

1. Direct Trauma: blunt force trauma (car accidents, sports collisions) / direct injuries from a surgery / inadvertent needle injection

2. Stretch Injuries: stretching nerve beyond 5-15% of normal length can lead to nerve fiber damage (1)

3. Compressive Injuries: fascial restrictions, localized swelling, and/or bone spurs

4. Repetitive Friction: fascial damage that leads to instability of the nerve that increases friction.

5. Metabolic Disease: systemic effect of poor metabolism

Recommended Reading

Non-surgical Peripheral Nerve Treatment

In this vlog, Dr. Jason Markle discusses advanced nerve hydrodissection and the use of platelet lysate.

Read/Watch more about advanced nerve hydrodissection >

Nerve Supplementation

Dr. Jason Markle goes over supplements that research has shown to help treat nerve issues.

Read/Watch about nerve supplementation >

Tibial Nerve Injury: Symptoms, Diagnosis, and Treatment Options

Dr. Markle goes over the symptoms, diagnosis, and treatment for tibial nerve compression.


Read/Watch about tibial nerve injury > 

Cyclist Syndrome / Pudendal Nerve Entrapment Treatment Options

Our clinic is situated between Boulder and Denver in Colorado, and both Boulder and Denver have a large cycling population!  With that being said, we often evaluate patients with Cyclist Syndrome, also known as Pudendal neuralgia (or Pudendal Nerve Entrapment).

Read More Cyclist Syndrome or Pudendal Nerve Entrapment Treatment Options >

Treating Nerve Injuries with Platelet Lysate

Nerve injuries are terrible and can be quite devastating. Muscles that did work just fine and without a second thought suddenly seem to lack control or just stop working altogether. At our clinic, we treat patients with nerve injuries using our advanced fourth-generation platelet lysate, and today we want to highlight this treatment as well as the story of one of our patients who had a radial nerve injury.

Read More >

Guyon’s Canal Treatment Options

Also known as Cyclists’ Palsy, Dr. Markle defines Guyon’s canal syndrome, its causes, symptoms, and treatment options.

Read about Guyon’s Canal and its treatment options >


Mahan, Mark A. ” Nerve stretching: a history of tension”, Journal of Neurosurgery JNS 132, 1 (2020): 252-259, accessed Oct 6, 2021,