In 2005, we were the first clinic in the world to invent highly specific image-guided procedures that used the body’s own bone marrow concentrate containing stem cells to treat common orthopedic problems, a field now called Interventional Orthopedics As international pioneers of these procedures that use the patient’s own cells and blood platelets (i.e. platelet-rich plasma or PRP), our board-certified medical doctors have more experience and have treated substantially more patients using these advanced Interventional Orthopedics procedures than any other provider or clinic across the globe. Our procedures can help you if you are in pain or, in more severe cases, provide an alternative to surgery.
I’ve been a patient of Dr Centeno for over 8 years. I have nothing but the highest complements for his professionalism, insights and overall care. Diagnosed with severe cervical spondylosis over 9 years ago, his semi-annual injections have kept me nearly pain free and clearly helped me avoid a multi-level cervical fusion, at least for the time being.
Frank B.
The staff at Centeno-Schultz are both professional and highly competent. My rather complex stem cell/PRP procedure went like clockwork with Dr. Jason Markle's expertise and incredible 'bedside' manner much appreciated. All my questions were answered as thoroughly as possible and the required steps in preparation, procedure and recovery were clearly communicated. Thank you. Now all that remains is the healing and return to normal function, a process in which I gladly offer my full participation.
Jonathan Z.
Can't say enough wonderful things not only about their technology but also the wonderful Doctors and staff! Doctor Schultz and team have provided major healing to my whiplashed entire spine and hip after 3 different motor vehicle accidents. I travel from Cincinnati to receive the best medical care from my Denver team. Keep doing what you.are doing. It has made a profound difference in my quality of life.
Marc W.
Dr. Markle has performed 3 separate procedures on my shoulders in the past 2 years. The results I have experienced are outstanding. I went from constant pain and limited activity with a torn rotator cuff in the my right shoulder back to full activity levels. I had the same SD Regenexx procedure performed on my left shoulder in December and am recovering nicely, hoping for the same outcome as the right.
Sarah S.
Dr. Markle is compassionate and thorough. He cares about the patient and how their life is being affected by their orthopedic issue. He looks at the big picture, and gives a clear explanation of the diagnosis as well as the plan of treatment. Dr. Markle is very knowledgeable and experienced. I would even consider him an expert in the field of orthopedic medicine and regenerative treatments like PRP and Stem cells. I only trust Dr. Markle with my orthopedic care and treatment. He has treated my cervical spine for issues like instability, bulging disks, and nerve issues. I cannot thank him enough for improving my neck and helping me get back to enjoying life.
Nancy C.
Dr Pitts demonstrates the height of professionalism and depth of knowledge treating my shoulder. While my visit was for my shoulder Dr. Pitts asked if I’d been in a car accident. I had some 15 years prior. He spent the time to inquire about the causes of my discomfort vs treatment I received (or rather, did not receive) previously. His recommended course of treatment was not limited to my shoulder but as well included my neck.
Dr. Pitts is genuinely likable, focused, responsive and most certainly one of the most intelligent and conversant medical authorities I’ve met. I am fortunate to have my stem cell treatment from this exceptional physician and am enjoying having full use of my arm again!
Lisa R.
Dr. Schultz and staff were exceptional in their professionalism and commitment to the best possible outcome for me. Dr. Shultz was wonderful, attentive, and efficient. I appreciated his attention to the whole picture of my injuries as well as the smallest details of my issues. I am very grateful to the exceptional care I received from Dr. Schultz and the entire staff at the Centeno-Schultz clinic. I would highly recommend anyone in need of orthopedic care to contact Regenexx first.
Sean M.
I'm giving the Centeno Schultz Clinic staff and Dr. Schultz 5 stars. The medical assistants and rest of the staff do an outstanding job with their procedures and communications. Aimee was especially helpful in scheduling my appointments and communicating with me via email, my preferred method. I feel very fortunate to have been referred to Dr. Schultz, he potentially saved me from having unnecessary hip surgery. Of the Doctors I have seen for my hip and back pain, he is by far the most intelligent and caring. I was impressed with the detail in which he read my MRI's. He is dedicated to finding the root causes of pain and treating for the best long term outcome. I have already recommended Dr. Schultz to several of my friends and family and will continue to do so.
Tanya S.
I would highly recommend Dr. Pitts. I’ve had my knees and elbow done. The PRP (or whatever they call theirs) on tennis/golf elbow was highly effective. The stem cells on the knees (lacking cartilage behind knee caps) were pretty effective, but only b/c I combined that with a great trainer (Brenna @KoaFit in Boulder) to redistribute the balance of strength in my legs (too much in front compared to what was in back).
Nathan Y.
I will admit I was a little skeptical at first. Dr. Hyzy did a great job of educating me and ensured me I was a good candidate for PRP. 8 weeks later I am working out and golfing regularly with no pain. I haven't been able to do that in years! Thanks Dr. Hyzy and the Regennex team!
The Nation’s Most Experienced Interventional Orthopedics Specialists
While many patients are looking for therapies that have been aggressively marketed, what they’re really looking for is a provider who has the clinical expertise to use cells taken from the patient’s body to help treat orthopedic problems without invasive surgery. With two Colorado locations, the Centeno-Schultz Clinic is the world headquarters for the International Regenexx Network and home to multiple research teams studying the safety and efficacy of various medical procedures using your body’s own platelets (PRP and platelet lysate) and bone marrow concentrate (containing stem cells). Our Broomfield office is conveniently located to those in Boulder and North Denver, while our Lone Tree office is conveniently located for those who live in South Denver and adjoining areas. We are the top regenerative orthopedic clinic in the United States, with industry-leading experience, published research, specialized Interventional Orthopedics training, and published outcome data. With dozens of peer-reviewed publications, we are recognized by our peers as educators and leaders in the field.
The Centeno Schultz Clinic, also called Regenexx Colorado, reinvests a portion of annual revenue into R&D and is home to a university-level, sophisticated clinical and lab research facility for the use of your body’s own platelets and cells. Our 12,000-foot facility houses a state-of-the-art clinic, including the latest in digital x-ray (fluoroscopy) and ultrasound imaging equipment, a large, ultramodern clean room for cell processing and counting, and a fellowship program where we educate young physicians in Interventional Orthopedics.
You can feel confident that you can trust the international pioneers of these procedures to treat many common orthopedic conditions using advanced image-guided procedures using your own cells.
Our Board-Certified & Fellowship trained physicians have helped more orthopedic patients using Interventional Orthopedics than any other regenerative medicine clinic in the world.
Learn about the Centeno-Schultz Clinic and our cutting-edge procedures from co-founder John Schultz, MD.
Jason Markle, DO discusses lumbar spine conditions, treatments, and the Centeno-Schultz Clinic procedures that may be able to help treat the underlying cause of your low back pain.
Looking for an alternative to ACL surgery? John Pitts, MD discusses treating ACL tears with PRP and bone marrow concentrate containing stem cells, and leaving surgery as the last resort.